Indoleamine 2,3-Dioxygenase (IDO) Inhibitors

IDO1

IDO2

IDO

Indoleamine 2,3-Dioxygenase (IDO) Inhibitors

Product Name	IDO1	IDO2	IDO	Purity
Epacadostat	IDO1, IC₅₀: 71.8 nM			99.66%
Indoximod			IDO, Ki: 19 μM	99.85%
Linrodostat	IDO1, IC₅₀: 1.1 nM			99.81%
NDs-IN-1	IDO-1
Palmatine chloride	IDO-1, IC₅₀: 3 μM (HEK 293-hIDO-1) IDO-1, IC₅₀: 157 μM (rhIDO-1)			99.81%
(Rac)-Indoximod			IDO	98.13%
Coptisine chloride			IDO, IC₅₀: 6.3 μM IDO, Ki: 5.8 μM	98.26%
PF-06840003	IDO-1			99.87%
IDO-IN-7	IDO1, IC₅₀: 38 nM			99.98%
Navoximod			IDO, EC₅₀: 75 nM IDO, Ki: 7 nM	99.99%
DP00477	IDO1, IC₅₀: 7.0 μM			99.03%
Palmatine hydroxide	IDO-1, IC₅₀: 3 μM (HEK 293-hIDO-1) IDO-1, IC₅₀: 157 μM (rhIDO-1)			99.64%
LY-3381916	IDO1			99.54%
IDO1/TDO-IN-4	IDO1, IC₅₀: 3.53 μM			99.23%
GNF-PF-3777		rhIDO2, IC₅₀: 1.8 μM rhIDO2, Ki: 0.97 μM		98.03%
IDO2-IN-1	IDO1, IC₅₀: 411 nM	IDO2, IC₅₀: 112		98.86%
PCC0208009			IDO, IC₅₀: 4.52 nM (in HeLa cell)	99.08%
PROTAC IDO1 Degrader-1	IDO1, DC₅₀: 2.84 μM IDO1, IC₅₀: 1.07 μM			98.17%
IDO5L			IDO, IC₅₀: 67 nM IDO, IC₅₀: 19 nM (in HeLa cell)	99.89%
IDO-IN-3			IDO, IC₅₀: 290 nM IDO, IC₅₀: 98 nM (in HeLa cell)	98.97%
BMS-978587	IDO-1			99.92%
Palmatine	IDO-1, IC₅₀: 3 μM (HEK 293-hIDO-1) IDO-1, IC₅₀: 157 μM (rhIDO-1)
IDO-IN-1			IDO, IC₅₀: 59 nM IDO, IC₅₀: 12 nM (in HeLa cell)	98.13%
IDO-IN-5			IDO, IC₅₀: 1-10 μM	99.90%
IDO-IN-8			IDO, IC₅₀: 1-10 μM	99.99%
BMS-986242	IDO1			99.42%
IDO-IN-6			IDO, IC₅₀: 1 μM	99.90%
Coptisine			IDO, IC₅₀: 6.3 μM IDO, Ki: 5.8 μM
IDO1 and HDAC1 Inhibitor	IDO1, IC₅₀: 69.0 nM
IDO-IN-9			IDO, IC₅₀: 11 nM IDO, IC₅₀: 1.8 nM (in Hela cell)
IDO-IN-11			IDO, IC₅₀: 180 nM IDO, IC₅₀: 14 nM (in Hela cell)
IDO1/2-IN-1	IDO1, IC₅₀: 28 nM	IDO2, IC₅₀: 144 nM		98.06%
IDO1-IN-17	IDO1, IC₅₀: 0.44 μM (in hela cells)
ZC0101	IDO1, IC₅₀: 0.084 μM
MMG-0358	IDO1, IC₅₀: 330 nM
CAY10581			IDO, IC₅₀: 55 nM
Roxyl-9	IDO1			99.22%
NAMPT/IDO1-IN-1	IDO1, IC₅₀: 233 nM
IDO1-IN-21	IDO1, IC₅₀: 0.64 μM
IDO1-IN-13	IDO1, IC₅₀: 30 nM
IDO1-IN-19	IDO1			98.52%
IDO1/TDO-IN-1	IDO1, Ki: 0.23 μM
NU223612	IDO1, Kd: 640 nM
1-Isopropyltryptophan	IDO1
IDO1-IN-15	IDO1, IC₅₀: 127 nM
AT-0174	IDO1, IC₅₀: 0.17 μM
IDO1-IN-2	IDO1, IC₅₀: 81 nM
IDO1-IN-16	IDO1, IC₅₀: 127 nM
IDO1-IN-14	IDO1, EC₅₀: 396.9 nM
Linrodostat mesylate	IDO1, IC₅₀: 1.1 nM
2-Hydrazinobenzothiazole	IDO1, IC₅₀: 8 μM			99.95%

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